CISPLATIN-ENCAPSULATED TRAIL-ENGINEERED EXOSOMES FROM HUMAN CHORION-DERIVED MSCS FOR TARGETED CERVICAL CANCER THERAPY

Cisplatin-encapsulated TRAIL-engineered exosomes from human chorion-derived MSCs for targeted cervical cancer therapy

Abstract Background Cisplatin (DDP) is an efficacious and widely applied chemotherapeutic drug for cervical cancer patients who are diagnosed as metastatic and inoperable, or desiring fertility preservation.Tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) selectively triggers cancer cells apoptosis by binding to cognate death r

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The flip side of multi-level marketing: A diagnosis of factors leading to the mass uptake of unregulated pyramid schemes in South Africa

This study sought to diagnose the factors leading to the mass uptake of unregulated pyramid schemes in South Africa.The study adopted an exploratory and qualitative research design.Face-to-face interviews were conducted with 20 respondents using a non-probability sampling technique known as purposive sampling.The respondents were drawn from the tar

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ON THE SACREDNESS OF THE NATURE IN GLOBAL RELIGIONS

Aim.The central aim is to consider the highly complex problem of interdependence of ecology and religion; determine the possibility of finding ways to revive nature protection traditions rooted in different religious systems; demonstrate the possibility of formation of ecological consciousness, ecological ethics as a prerequisite for sustainable de

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Are hepatocellular neoplasms with a Cytokeratin 7-positive pseudoglandular pattern destined for malignant transformation? A comparison of two cases

The distinction between hepatocellular adenoma and carcinoma can be challenging.Many histologic features are proposed to be indicative of hepatocellular carcinoma including pseudoglandular formation with positive keratin staining.We hereby report two cases of hepatocellular neoplasms with the Bong Bowls same histopathologic features that received d

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